Dr. Md. Rasel Prank
Chattogram Veterinary and Animal Sciences University
Bangladesh
Abstract Title: Emerging Trends in Lumpy Skin Disease Prevalence in Bangladesh: A Comprehensive Systematic Review and Meta-Analysis (2019–2025)
Biography:
Dr. Md. Rasel Prank is a Lecturer in the Department of Anatomy and Histology at Chattogram Veterinary and Animal Sciences University (CVASU), Bangladesh. He earned his Doctor of Veterinary Medicine (DVM) in 2022, graduating first in his class, and completed his Master of Science in Anatomy in 2025 with highest distinction. His research focuses on cellular and molecular biology, immunohistochemistry, and veterinary anatomy, with multiple publications in international journals. Dr. Prank has received several academic awards, including the Dean’s Award, and leads projects on genomic analysis and reproductive biology, contributing significantly to veterinary research and education in Bangladesh
Research Interest:
Lumpy Skin Disease (LSD) is a highly contagious, transboundary viral disease of cattle, characterized by rapid cross-border transmission and significant production losses. This systematic review and meta-analysis summarize the status of LSD in Bangladesh. A comprehensive literature search spanning 2019 to 2025 was conducted across multiple databases, including Science Direct, Scopus, Google Scholar, and PubMed. After meticulous assessment of quality bias, employing inclusion and exclusion criteria, 17 studies were included in the present study for analysis. Raw data were extracted in Microsoft Excel and then imported into STATA-18. The random effects model was used to pool estimates of outcomes at a 95% confidence interval. Publication bias was checked using funnel plots for standard error augmented by Freeman and Tukey’s tests. The pooled average prevalence of LSD was 22% (95% CI: 0.16-0.30) with varied sample sizes across studies, the largest comprising 2,858 samples and the smallest consisting of 53 samples. A subgroup meta-analysis assessed LSD prevalence based on study year, design, disease occurrence, and diagnostic methods. The highest prevalence (34%, 95% CI: 0.30-0.38) was recorded in 2020-2021, while the lowest (2%, 95% CI: 0.02-0.03) was observed elsewhere. Pooled prevalence by study design was 24% (cross-sectional) and 2% (retrospective). Disease occurrence analysis showed 3% in endemic areas and 26% in outbreaks. Diagnostic method-based prevalence was 21% (clinical symptoms), 32% (PCR), and 21% (PCR & clinical symptoms). In multivariable meta-regression analysis, the prevalence of LSD was significantly (P<0.0001) associated with study design, disease occurrence, and the type of diagnostic methods used. The analysis of effect sizes and standard errors indicated publication bias in LSD prevalence, as evidenced by the asymmetric funnel plot. This meta-analysis highlights variations in LSD prevalence based on multiple factors, emphasizing the role of diagnostic methods in accurate disease detection. Therefore, effective disease control measures should include cattle vaccination, strict quarantine protocols, and comprehensive vector management strategies.